What is Xofigo?
Xofigo injection is indicated for the treatment of patients with castration-resistant
prostate cancer (CRPC), symptomatic bone metastases and no known visceral
Xofigo can cause fetal harm when administered to a pregnant woman based
on its mechanism of action. Xofigo is not indicated for use in women.
Xofigo is contraindicated in women who are or may become pregnant.
Is Xofigo Right For You?
Xofigo gives off radiation that helps kill prostate cancer cells.
- Xofigo contains the radioactive material radium 223. It goes to areas in
your bones that are growing quickly, just like calcium does. Bone metastases
are one of those rapidly growing areas
Even though Xofigo gives off a strong energy, it has a short range that
does limited damage to health cells around it
- Xofigo can be absorbed by other organs, primarily the bone marrow and digestive
system, which may result in side effects in those healthy tissues.
Safety With Xofigo
There are certain things you should be aware of when being treated with Xofigo.
- Do not take Xofigo if you are pregnant or may become pregnant. Xofigo can
harm your unborn baby. Women who are pregnant or may become pregnant should
not come in contact with Xofigo without protection, such as gloves
- If you suffer from bone marrow problems (a decrease in blood cell production
in the bone marrow), your healthcare provider will decide if treatment
is appropriate. In a clinical trial, some patients had to permanently
discontinue therapy because of bone marrow problems.
Tell your healthcare provider if you:
- Are receiving any chemotherapy or any extensive radiation therapy. The
use of chemotherapy while taking Xofigo is not recommended
- Have any other medical conditions
The most common side effects of Xofigo include:
- Swelling of the arms or legs (peripheral edema)
- Low blood cell counts
It's also important that you talk to your healthcare provider about
any side effects you may have while receiving your treatment that bother
you or do not go away. If you have any questions about your care, be sure
to contact your urologist at Urology Associates, P.C.