Xofigo

What is Xofigo?

Xofigo injection is indicated for the treatment of patients with castration-resistant prostate cancer (CRPC), symptomatic bone metastases and no known visceral metastatic disease.

Xofigo can cause fetal harm when administered to a pregnant woman based on its mechanism of action. Xofigo is not indicated for use in women. Xofigo is contraindicated in women who are or may become pregnant.

Is Xofigo Right For You?

Xofigo gives off radiation that helps kill prostate cancer cells.

  • Xofigo contains the radioactive material radium 223. It goes to areas in your bones that are growing quickly, just like calcium does. Bone metastases are one of those rapidly growing areas
  • Even though Xofigo gives off a strong energy, it has a short range that does limited damage to health cells around it
    • Xofigo can be absorbed by other organs, primarily the bone marrow and digestive system, which may result in side effects in those healthy tissues.

Safety With Xofigo

There are certain things you should be aware of when being treated with Xofigo.

  1. Do not take Xofigo if you are pregnant or may become pregnant. Xofigo can harm your unborn baby. Women who are pregnant or may become pregnant should not come in contact with Xofigo without protection, such as gloves
  2. If you suffer from bone marrow problems (a decrease in blood cell production in the bone marrow), your healthcare provider will decide if treatment is appropriate. In a clinical trial, some patients had to permanently discontinue therapy because of bone marrow problems.

Tell your healthcare provider if you:

  • Are receiving any chemotherapy or any extensive radiation therapy. The use of chemotherapy while taking Xofigo is not recommended
  • Have any other medical conditions

The most common side effects of Xofigo include:

  • Nausea
  • Diarrhea
  • Vomiting
  • Swelling of the arms or legs (peripheral edema)
  • Low blood cell counts

It's also important that you talk to your healthcare provider about any side effects you may have while receiving your treatment that bother you or do not go away. If you have any questions about your care, be sure to contact your urologist at Urology Associates, P.C.

For more information regarding Xofigo visit the Bayer site here.

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